New tool may help researchers predict cognitive decline with Parkinson's disease

A new tool from researchers at Harvard Medical School may allow investigators to predict cognitive decline in people with Parkinson's disease (PD), which could help design clinical trials and test new therapies. The tool uses an algorithm combining varied personal details -- age at onset, baseline score on the Mini Mental State Examination, years of education, motor exam score, sex, depression, and GBA mutation status.
Susan Lindquist

Lindquist leaves behind Parkinson's interactome as her parting gift

For the many genes and proteins involved in Parkinson’s disease, it’s a small world. Basically, they are all at least friends of friends. Leveraging connections between yeast genes to infer links between human genes, researchers led by the late and beloved Susan Lindquist of the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, have just made that clear.
2015 focus session on Parkinson's