Home Page - BWH Parkinson Research

Investigating LRRK2 as a common genetic contributor to Parkinson's disease

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October 19, 2017

Dr. Jie Shen and her team describe an essential role of LRRK in the brain during aging that may help shed light on the causes of PD.

Could repurposed asthma drugs treat Parkinson’s disease?

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September 16, 2017

Team makes a surprising discovery that some asthma medicines may also hold the potential to treat or help prevent Parkinson’s disease.

New tool may help researchers predict cognitive decline with Parkinson's disease

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June 23, 2017

A new tool from researchers at Harvard Medical School may allow investigators to predict cognitive decline in people with Parkinson's disease (PD), which could help design clinical trials and test new therapies. The tool uses an algorithm combining varied personal details -- age at onset, baseline score on the Mini Mental State Examination, years of education, motor exam score, sex, depression, and GBA mutation status.

Lindquist leaves behind Parkinson's interactome as her parting gift

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February 11, 2017

For the many genes and proteins involved in Parkinson’s disease, it’s a small world. Basically, they are all at least friends of friends. Leveraging connections between yeast genes to infer links between human genes, researchers led by the late and beloved Susan Lindquist of the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, have just made that clear.