Xianjun Dong

Xianjun Dong, Ph.D.

Instructor in Neurology · Harvard Medical School
Director of Computational Neuroscience · Brigham and Women's Hospital


Working on the human genome as a computer geek, Dr. Dong was quite facinated by the human brain — the most complex organ controlled by a single copy of DNA. How could this happen? To decode the top secret in brain, Dr. Dong is passionate about developing and applying Deep Learning methods to understanding transcriptional regulation, via integrating genomic, transcriptomic, epigenetic, and clinical data from both healthy subjects and patients with neurological diseases.

Dr. Dong has 20+ publications in top peer-reviewed journals with 10,000+ citations and H-index of 20. He is familiar with various next-generation sequencing data analyses (e.g. ChIPseq, RNAseq, RNA-PET, CAGE, and WGS), Linux/Unix system, R/Perl programming, algorithm and web tools development. He was an active member in the ENCODE consortium. His latest work about enhancer RNAs in dopamine neurons is soon published in Nature Neuroscience. Dr. Dong was recently awarded by the American Parkinson Disease Association (APDA).

Dr. Dong received a PhD degree in Bioinformatics in University of Bergen (supervisor: Boris Lenhard) and a Postdoctoral fellowship in Bioinformatics and Integrative Biology in University of Massachusetts Medical School. Dr. Dong is an Instructor in Harvard Medical School and acts as the Director of Deep Learning Neuroscience in the Precision Neurology Program at Brigham and Women’s Hospital. He also runs a weekly Bioinformatics Club in BWH. See his website for more details: sterding.com